The Dangers of Polypharmacy in Elderly Patients

JAMA Internal Medicine

The Dangers of Polypharmacy in Elderly Patients
Jacques Turgeon, BPharm, PhD; Veronique Michaud, BPharm, PhD; Lauren Steffen, PharmD
JAMA Intern Med. 2017;177(10):1544. doi:10.1001/jamainternmed.2017.4790

To the Editor In a recent issue of JAMA Internal Medicine, Carroll and Hassanin published a Teachable Moment that embodies the importance for health care practitioners to reduce polypharmacy and prevent adverse drug events. Although we support their conclusions, we provide additional explanation regarding underlying causes of bradycardia and hypotension in patients besides unintentional metoprolol overdose.