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Adverse Drug Events in the U.S.: Overview and Prevention

Adverse Drug Events

Adverse drug events (ADEs) are responsible for 10% of all hospital admissions in the U.S. ADEs lead to longer hospital stays, increased healthcare expenditures, and compromised clinical outcomes.1 Overall, medication-related morbidity and mortality costs the U.S. healthcare system more than $528 billion annually (2016 est.).2 Polypharmacy is a key risk for ADEs—the risk increases by 7-10% for each medication a person takes.3  

Multi-drug Interactions

Drug interactions are a subject of particular concern, with 36% of the U.S. population currently using 5 or more medications.4 Traditional models identify drug-drug interactions but fail to account for cumulative effects related to complex regimens and multi-drug interactions.

The MedWise Risk Score™ is a clinically validated ADE risk-assessment tool that can predict increases in risk for mortality, ADEs, ED visits, and hospital admissions. The MedWise Risk Score is a benchmark that can be used to personalize medication regimes to lower risk and prevent ADEs for individual patients. Our goal is to help prevent ADEs, thereby improving clinical outcomes and reducing the cost of healthcare.

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